This study uses a two factor design (temperature and humidity) to investigate volumetric performance (precision and trueness) at environmental conditions from 15 °C to 30 °C and 30% to 80% relative humidity. Nine environmental conditions were tested, the mid point, four corner cases and four edge cases. Replicate testing was performed at the mid point and corner cases.
When your tests can impact criminal cases, help labs confirm that a sample belongs to a specific patient, or help verify or refute paternity, data quality matters. Your answers can't be wrong. Knowing that your pipettes are performing within specifications is a critical part of ensuring data quality, but for Sorenson Genomics, managing pipette calibration was a challenge.
Research shows that up to 30 percent of pipettes and other liquid delivery devices currently in service are not performing within expected tolerances at any given moment. The risk of non-performing liquid delivery devices is compounded by the ever smaller volumes typically handled in today’s laboratories. This means that volumes that are inaccurate by just a few microliters can have significant effects on results.
Working with Artel, Takeda developed an analyst qualification program using the same technology it uses to verify and calibrate its robotic liquid handlers. The implementation of the comprehensive program not only reduced assay failures but also helped the company transfer assays from bench to automation by using the same measurement standard for each phase of the process.