September 23, 2013

US Pharmacopeia Proposes Changes to Weighing Chapters

Weighing is one of the most fundamental of laboratory tasks, and careful weighing is a central pillar supporting the generation of high-quality laboratory results. New proposals from […]
September 23, 2013

CMS Offers EP23 as Risk-Based Option for Clinical QC Plans

In two memoranda dated November 4, 2011 and March 9, 2012 the US Centers for Medicare and Medicaid Services (CMS) have informed laboratories of their intention to provide a new […]
September 23, 2013

When Do Guidelines Become Requirements?

MIQE Makes a Difference in PCR A guideline such as Minimum Information for Publication of Quantitative Real-time PCR Experiments (MIQE) is a good example of how a science-based guideline […]
September 23, 2013

New ISO Standard Answers Growing Need for Data Integrity in the Laboratory

Technologies often develop more quickly than regulatory agencies can respond. This is especially true in drug discovery and development due to the rapid pace of new technological […]
September 23, 2013

Taking Control of Your Quality Control

Navigating Regulations and Standards for Liquid Delivery Verification Consider a quality control laboratory that processes 10 to 20 samples per day and releases as many as […]
September 23, 2013

3 Tips to Aid Assay Transfer

These guidelines can improve the success of assay transfers within and between laboratories Ensuring that assays give the same results on different platforms or in different […]
September 23, 2013

Optimization of Automated Liquid Handlers

Regular Instrument Performance Checks Help Ensure Accurate Reagent Volume Transfer Over the past 20 years, laboratories around the world have been turning to liquid handling robots to increase […]
September 23, 2013

Climb Every Mountain: Extreme Pipetting I

The Effect of Barometric Pressure on Data Integrity One cold day in early winter, a group of scientists prepare to trek to the top of Mount […]
September 23, 2013

Extreme Pipetting II: Thermal Exploration

The effect of fluid temperature on data integrity After studying the effects of barometric pressure on pipette volumes atop New Hampshire’s Mount Washington—home of the world’s […]
September 20, 2013

Extreme Pipetting III: Death Valley Data

The effect of dry heat on laboratory data As the Artel extreme pipetting expedition team set out for Mission 3, only one thing was certain: it was […]