January 11, 2017

Ten Tips for Proper Pipetting

This American Laboratory article covers ten fundamental steps – and explains their significance – to improve and standardize the skills of those who operate pipetting instruments.
February 23, 2016

SURVEY REPORT: Data quality, variability, and reproducibility

From the Reproducibility Initiative to F1000 Research’s Preclinical Reproducibility and Robustness channel, much attention in the life science community has been focused on study reproducibility. These […]
September 23, 2014

Minimizing Liquid Delivery Risk: Pipettes as Sources of Error

Research shows that up to 30 percent of pipettes and other liquid delivery devices currently in service are not performing within expected tolerances at any given moment. The risk of non-performing liquid delivery devices is compounded by the ever smaller volumes typically handled in today’s laboratories. This means that volumes that are inaccurate by just a few microliters can have significant effects on results.
September 23, 2014
liquid handling

Minimizing Liquid Delivery Risk: Automated Liquid Handlers as Sources of Error

To reduce liquid handling error, laboratories must implement regular calibration programs and verification checks for volume transfer accuracy and precision and to quickly identify those systems that are failing. The evaluation method should be standardized, fast, easy to implement, and minimize instrument downtime and required resources.
July 16, 2014
pipetting technique

Best Practices for the Use of Micropipets

Every day, air-displacement pipets are used to quantitatively dispense sample and reagent aliquots for reaction, routine analyses, and specialized tests. Since concentrations of biological and chemical components in the prepared samples for analyses and assays are volume-dependent, incorrectly performed pipetting steps will directly impact the transferred volumes, and hence, the test results.
April 7, 2014
Effect of Liquid Handler Accuracy on Assay Perfromance

Effect of Liquid Handling Accuracy on Assay Performance

This study illustrates how optimization of both liquid-handling accuracy and precision is critical to assay performance. The study was designed to examine (1) liquid-handling performance and […]
November 12, 2013

DMSO Sample Solution for Liquid Handler Performance Verification

Dimethyl sulfoxide (DMSO) has become one of the most important solvents used for high-throughput screening (HTS) and compound management applications due to its ability to readily […]
October 28, 2013

Five Good Reasons: the argument for pipetting technique training

Liquid handling quality assurance is a critical component of an effective laboratory quality program. While quality assurance efforts in liquid handling typically place much emphasis on pipette calibration, repair, and maintenance, ensuring […]
October 23, 2013

8 Easy Steps for Performing Pipette Preventive Maintenance

Pipettes are precision devices that require care for consistent results. Performing preventive maintenance routinely will help to minimize malfunctions and keep your instruments in good operating condition. Depending […]
October 20, 2013

Artel Extreme Pipetting Expedition: Measuring the Impact of Common Environmental Conditions on Laboratory Data Integrity

A team of scientists journey to extreme locations to demonstrate how even the most typical laboratory conditions can wreak havoc on pipette accuracy.