Not all liquid types behave like water. Trying to optimize a liquid class on any automated liquid handler can be a challenging task especially if the solution is non-ideal. Due to a liquid’s unique rheological properties, compounded by the absolute need for accurate and precise assay results, Artel helps solve this problem by continuing to develop testing solutions for use on our MVS system. Our two most recent solutions closely mimic two common biological liquid types: PCR master mix and serum. These products are specifically engineered to assist in liquid class optimization and calibration. We will overview the technical aspects of these new products as well as illustrate how to use them effectively in automated assay workflows.