Resource Library: Knowledge and practical liquid handling tips you can put into practice

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10 Tips To Improve Your Pipetting Technique
The experts at Artel demonstrate, in detail, how your pipetting technique and the performance of your pipette can be significantly improved.
Viscous Poster
Pipetting Viscous Solutions
The Pipetting Viscous Solutions poster provides guidance on pipetting solutions and helps in understanding that viscosity is the measure of a liquid’s resistance to flow.
Minimize Variability in your NGS assay
This webinar presents methodologies for increasing throughput, lowering costs and improving reproducibility for your automated assays.

Verifying the accuracy and precision of liquid handlers is essential for assay reliability

By Schork, S. - Artel, Jenkins, J., Schenker, B. - TTP Labtech
Introduction Assay-ready plates are becoming key to maximizing throughput and assay robustness for many HTS departments. These plates contain test compounds prepared at specific concentrations…

ATS-100 Acoustic Transfer System calibration using Artel MVS and DMSO Range E dye: A practical approach to developing calibration curves

By Scheibe, D., Palan, J., Khovananth, K.
Overview The ATS-100 transfers one or more droplets of a given fixed size (e.g. 1nl, 2.5nl, 10nl, etc.) in multiples necessary to attain the desired…

Pipetting Comparison of DMSO Versus Aqueous Solutions as Measured Using Dual-Dye Technology

By Parshley, R., Bradshaw, J., Albert, K.
 Abstract DMSO (dimethyl sulfoxide) has become one of the most important solvents used throughout pharmaceutical and life science laboratories. This is particularly true for high-throughput…

Accuracy and Precision in Low Volume Liquid Transfers

By Tam, S., Rodrigues, G. - Artel, Forbush, M. - EDC Biosystems
Introduction Acoustic transfer systems operate by ejecting a rapid fire stream of tiny discrete droplets, with each droplet adding a few nanoliters to the total…

DMSO Sample Solution for Liquid Handler Performance Verification

By Parshley, R.
Dimethyl sulfoxide (DMSO) has become one of the most important solvents used for high-throughput screening (HTS) and compound management applications due to its ability to…

Best Practices for Assessing Nanoliter Transfer Performance for Labcyte Echo Liquid Handlers

By Bradshaw, J., Albert, K. - Artel, Mock, M., Shieh, J. - Labcyte
Abstract Acoustic  drop ejection (ADE) technology enables  low- nanoliter  transfers  for high-throughput screening applications. Verifying  the absolute transferred volume  and the well-to-well reproducibility of the…

Rapid Accuracy and Precision Assessment of DMSO Compound Solutions Transferred with Pocket Tips

By Albert, K., Kroncke, D.
Abstract Performing assays with liquid handling equipment to rapidly test and screen compounds is essential to drug discovery and other biopharma processes. In order to…

Verifying Mosquito Nanoliter Liquid Dispensing

By Schenker, B., Albert, K., Knaide, T.
Abstract Assay-ready plates are becoming key to maximizing throughput and assay robustness for many HTS departments. These plates contain test compounds prepared at specific concentrations…

Development of a 100% DMSO Sample Solution for Liquid Handler Performance Verification

By Parshley, R., Bradshaw, J., Rodrigues, G., Albert, K., Olson, K., Rumery, D.
Abstract DMSO (dimethyl sulfoxide) has become one of the most important solvents used for high-throughput screening (HTS) and compound management applications due to its ability…

Automation of Nanoliter Volume Transfers

By Fay, J., Williams, E., Mosser, S., Harrell, C., Calamari, A., Mullen, F., Harkins, T., Bednar, R.
Doing More With Less Introduction To facilitate the discovery and refinement of lead compounds, our laboratory known as the Facility for Automation and Screening Technology…

Accuracy Matters When Quantitative, Manually-pipetted Assays Graduate to Automation

By Albert, K., Knapp, L.
A Story in Diagnosing and Troubleshooting Abstract It is often the case that assays are initially performed on the benchtop  using handheld  pipettes  before they…

Accuracy of Serial Dilutions Tested Over a Large Dilution Range

By Knaide, T., Parshley, R., Bradshaw, J., Curtis, R.
ABSTRACT The process of serially diluting solutions in microplates is common for many assays including preparation of dose response curves for IC50, drug efficacy testing,…

Verifying Dispensing Performance & Optimizing Accuracy on a Redd&Whyte Preddator Nano-bulk reagent Dispenser

By Poole, R., Redd & Whyte, Albert, K., Artel
Abstract This application note discusses an approach to verify and optimize the dispensing accuracy on a Redd & Whyte Preddator dispenser using measurement information from…

Creating and Testing Custom Alternative Solutions

By Albert, K.
Introduction Custom test liquids using assay-specific reagents can be prepared and employed to assess volume transfer performance of a liquid handler using the Artel MVS®…

Volume Verification Using Any Microtiter Plate or Small Volume Container Such as a Tube or Vial

By Albert, K.
Abstract This application note discusses methods for measuring target volumes (10 nL - 200 μL) dispensed into any microtiter plate or small volume container using…

Painless Nanoliter-Transfer Accuracy Inspection for Busy Screeners

By Albert, K., Mock, M., Shieh, J.
Abstract Acoustic droplet ejection first provided low-nanoliter transfers for high-throughput screening applications in 2004. At that time, there were no methods that could quickly and…

Verifying Liquid Handler Performance for Complex or Non-Aqueous Reagents: A New Approach

By Keith J. Albert, John Thomas Bradshaw, Tanya R. Knaide, and Alexis L. Rogers
Multichannel volume dispensing devices, such as automated liquid handlers, are widely used in drug discovery assays and other high-throughput screening processes. The performance of these…

Ethanol Solutions for MVS® Volume Verifications

By Keith J. Albert, Ph.D.
Introduction Ethanol is used in pharmaceutical and other life science laboratories for innumerable experimental protocols. Ethanol is often combined and/or used as an additive in…

Glycerol Solutions for MVS® Volume Verifications

By Keith J. Albert, Ph.D.
Introduction Glycerol plays an important role in many industries and because of its physical and chemical characteristics, it is used extensively in life science industries.…