Resources: Knowledge and practical liquid handling tips you can put into practice

We have collected data and information that focus on optimized assay workflows, as well as automated liquid handling and pipetting processes – all of which is compiled in the resources below. If you would like more details on how Artel can support your assay, don’t hesitate to reach out— call or email - we are here to help
Speed Assay Development
Process Optimization for Assays - Whitepaper
Find out how by downloading this new White Paper on using process optimization to reduce assay variability and improve productivity.
Pipetting viscous solutions poster
Pipetting Viscous Solutions
The Pipetting Viscous Solutions poster provides guidance on pipetting solutions and helps in understanding that viscosity is the measure of a liquid’s resistance to flow.
Troubleshooting Automation
Troubleshooting Automation
This Troubleshooting Automation poster provides guidance on how to identify common problems so you can get the best performance out of your liquid handling platforms.

An Easy Approach to Optimizing an Automated Liquid Handler Using PlasProxy™ QualAssure® Solutions with the MVS®

By Morgan Karnes, Michael Grimaldi
Abstract This application note demonstrates an approach for rapidly optimizing a liquid class to dispense PlasProxyTM – a new MVS® QualAssure® solution that mimics the…

Using the MVS to Measure Residual Volumes Remaining in a Plate After Sample Aspiration: General Approach

By Kevin Khovananth, Jim Neilsen, Keith J. Albert, PhD.
Abstract The purpose of this application note is to demonstrate an alternative use for the Artel MVS® Multichannel Verification System. As opposed to measuring the…

An Assessment of the Volumetric Performance of the The MANTIS® Liquid Handler Using the Artel MVS® Multichannel Verification System

By Kristi Allen, Thomas Rawlins, Dmitry Rodinov
Introduction Since the inception of the variable volume pipette in the 1960s, researchers have been sacrificing the precision of their liquid transfers for ease of…

I-DOT One & the Artel MVS®

By Mario Graeve, Christopher Laske, Stefan Schork
Abstract The Immediate Drop on Demand Technology (I-DOT) is a new approach for non-contact low volume dispensing, developed at the Fraunhofer Institute for Manufacturing Engineering…

Low Volume Liquid Measurement Testing with Beckman Coulter’s Biomek i-Series Automated Workstation using the Artel Multichannel Verification System (MVS®)

By Dana Campbell
Abstract This application note provides performance testing results obtained at the low volume range capability of Beckman Coulter’s Biomek i-Series Automated Workstation. The Artel MVS…

Optimizing Accuracy Performance of a Thermo Scientific Matrix WellMate Dispenser Using the Artel MVS®

By K. J. Albert
Abstract This application note discusses an approach for optimizing pipetting accuracy of a stand-alone Thermo Scientific Matrix WellMate dispenser by using the Artel measurement information.…

Performance assessment of the VIAFLO 96 handheld 96-channel pipette

By Rachel Parshley, Michael Beier
Introduction The standard method of determining a pipette’s liquid delivery performance is measuring the weight of the transferred liquid. Every channel of a multichannel pipette…

Dispensing Precision and Accuracy for the JANUS Varispan Workstation

By Marcus Patterson
Abstract Today’s biotech, pharmaceutical, environmental, clinical research, and  agricultural laboratories employ a diversity of applications and  depend more  and  more  on automated systems to address…

Volume Verification of Hamilton MICROLAB® STAR and NIMBUS Automated Liquid Handlers

By Doyle Stewart, Rick Luedke, Barry Godowsky, Keith J. Albert, PhD
Abstract A precise and accurate  means for conducting volume verification of automated  liquid handlers is an important requirement in life science laboratories, which need to…

Using the PCS to Calibrate the Beckman Coulter Biomek 3000

By Dana Campbell, Matt Wilkinson, PhD
Introduction Ensuring that pipetting devices (both manual and automated) are performing properly is often a regulatory requirement. Many of those labs that are not required…

Verifying Dispensing Performance & Optimizing Accuracy on a Redd&Whyte Preddator Nano-bulk reagent Dispenser

By Roger Poole, Keith J. Albert, PhD
Abstract This application note discusses an approach to verify and optimize the dispensing accuracy on a Redd & Whyte Preddator dispenser using measurement information from…

Pipetting Performance Testing of a Beckman Coulter Biomek 4000

By Tanya Knaide, Dana Campbell
Abstract A common interest in all areas of life science: lower costs and reduce repeat testing. Removing sources of variability from test processes reduces error…

Optimizing Accuracy Performance on a Beckman Coulter Biomek

By Keith J. Albert, PhD
Abstract This application note discusses one approach for optimizing pipetting accuracy on a Beckman Coulter Biomek liquid handler using MVS measurement information. Pipetting accuracy can be…

Optimizing Accuracy Performance on an Agilent Bravo Platform

By Keith J. Albert, PhD
Abstract This application note discusses one approach for optimizing pipetting accuracy on an Agilent Bravo liquid handler using MVS® Multichannel Verification System measurement information. Although…

Evaluation of the Eppendorf epMotion Pipetting Tools

By Jesse Cassidy, Tanya Knaide, Rachel Parshley, Cheng Lui, PhD
Introduction With budgets forever tightening and patient samples being limited, increased efficiency and reduction of repeat testing has become a common goal of almost all…

Creating and Testing Custom Alternative Solutions

By Keith J. Albert, PhD
Introduction Custom test liquids using assay-specific reagents can be prepared and employed to assess volume transfer performance of a liquid handler using the Artel MVS®…

Integration of Liquid Handler Quality Control Into the HTS Daily Routine

By Alexander Hochreiner, Stefan Schork, PhD, Matt Wilkinson, PhD, Bernhard Ellinger, PhD
Abstract This application note describes how the MVS® Multichannel Verification System can be used to assess the performance of the liquid handlers integrated into a PerkinElmer…

Performance Qualification of an Automated Plate Washer

By Kevin Khovananth, Tanya Knaide, Keith J. Albert, PhD
Introduction An integral, yet often overlooked, procedure with any given assay, washing steps are vital to ensure reaction quality and integrity particularly when conducted in…

Quantifying the Impact of Pipette Tip Type Using Dual Dye Ratiometric Technology

By Tanya Knaide, Keith J. Albert, PhD
Introduction All pipette tips are not created equal, nor are all assays. Failure to use proper tips for a given type of pipette can lead…

Measuring Residual Volumes Remaining in a Plate After Sample Aspiration

By Kevin Khovananth, Jim Neilsen, Keith J. Albert, PhD
Abstract The purpose of this application note is to demonstrate an alternative use for the Artel MVS® Multichannel Verification System. As opposed to measuring the…

Running MVS Volume Verifications in Batches, Storing Bar Codes, and Creating Task Templates

By Keith J. Albert
Introduction A Batch method, or Batch template, in MVS Data Manager version 2.2+ is a stored sequence of verification tasks comprising as many devices, plate…

Mixing Efficiency of Q-Instruments Bioshake 3000® Plate Shaker

By Tanya Knaide
Introduction Mixing of solutions in 384-well microplates is a challenging, yet highly important task for many laboratories and assays. Effective mixing is of particular importance…

Volume Verification Using Any Microtiter Plate or Small Volume Container Such as a Tube or Vial

By Keith J. Albert
Abstract This application note discusses methods for measuring target volumes (10 nL - 200 μL) dispensed into any microtiter plate or small volume container using…

Executing an MVS Volume Verification of a Tecan EVO Using EVOware Software

By Alexis L. Rogers
Introduction This paper describes how to run or call an Artel MVS® Multichannel Verification System volume verification from another program or application. The MVS Data Manager…

Evaluation of Forward & Reverse Mode Liquid Handling Techniques

By Tanya Knaide
Introduction Traditionally, precision of volume dispensing has received more focus than accuracy, making the latter overlooked. This study highlights the importance of understanding both accuracy…

Artel MVS as a Tool for Measuring Liquid Mixing Efficacy in Microplates

By Tanya Knaide, Rachel Parshley, Matt Wilkinson, PhD
Abstract You wouldn’t bake a cake without mixing the ingredients first, yet when important assays are being conducted the liquids dispensed into a microplate are…

Cybi®-Selma – Basic Information

By Cybio
Introduction CyBi®-SELMA is a semi-automatic pipettor for quick, precise and reproducible processing of 96-well and 384-well microplates. Equipped with 96 or 384 parallel working tips…

Measuring the Precision and Accuracy of the Cybi®-Well vario

By Undisz, K., Hanegraaff, I., Schork, S., Knaide, T.
Introduction In laboratory automation precise and accurate liquid handling over a large volume range is essential to meet the challenges of modern drug discovery and…

Measuring the Accuracy and Precision of the epMotion 5070 Workstation

By Spaulding, B., Bradshaw, J., Albert, K., Eggert, H.
Introduction In response to the need to automate molecular biology methods, automated liquid handling technology has been the focus of extensive research and development. The…

Ethanol Solutions for MVS® Volume Verifications

By Keith J. Albert, Ph.D.
Introduction Ethanol is used in pharmaceutical and other life science laboratories for innumerable experimental protocols. Ethanol is often combined and/or used as an additive in…

Glycerol Solutions for MVS® Volume Verifications

By Keith J. Albert, Ph.D.
Introduction Glycerol plays an important role in many industries and because of its physical and chemical characteristics, it is used extensively in life science industries.…